Different Solvent of Phytochemical Screening and antibacterial activity of Xeromphis nilotica cortex extract

Abstract

The species Xeromphis nilotica belong to family Rubiaceae locally known as (Shagarat almafeen ),the aims of this study is to determine the phytochemical screening and antibacterial activities of Xiromphis nilotica cortex. This present study was carried out in Khartoum state-Sudan, during March 2019. Phytochemical activities were investigated to detect the effects of antibacterial; this plant was collected from Elsalihen area, locality of Algoze, South Kordofan State, western Sudan. The dried cortex of Xeromphis nilotica was extracted successively with (Ethanol, Ethyl acetate , methanol and distil water,). The phytochemical screening carried out on four different extracts of species cortex and it contain amount of secondary metabolize such as ( alkaloids, Carbohydrate Tannins, Phenol, Sterols & Triterpenes, Saponin, Flavonoids ,Quinine ,Amino acid and Protein were studied .The antibacterial activity of extracts were evaluated against four standard bacteria (Gram positive; Bacillus subtilis, Staphylococcus aureus) and (Gram negative; Escherichia coli, Pseudomonas aeruginosa) and the results showed that there are high inhibition zone (21-19) in ethanol and ethanol extract and low in habitation zone in water extract in all concentration